MCB 406        Gene Expression & Regulation (CRN: 62528)  (Spring Semester)

Course description:

MCB 406 is a lecture-discussion course that provides in-depth and up-to-date coverage of gene expression and regulation. Lectures are centered on the principles of regulating gene expression in eukaryotic cells. The course covers molecular mechanisms of the key gene expression events including transcription, RNA processing, mRNA localization, translation and degradation, as well as macromolecule structures and functions in gene expression and regulation.  Applications of these principles in medicine and therapeutics such as aging, cancer biology and drug design are also discussed.

Prerequisite: MCB 354

Course Objectives:

• Understand molecular mechanisms of the key gene expression events in eukaryotic cells.
• Use chemistry and biochemistry knowledge to explore interdisciplinary research on gene expression.
• Understand the many roles of RNA in gene expression.

• Gain awareness of gene expression in therapeutics including drug design.
• Develop skills for understanding and analyzing the primary scientific literature.
• Develop skills for communicating scientific information at an advanced level.